The Science Behind OPT9™
OPT9™ is a term LifePharm uses to describe its core ingredient. A proprietary blend which is about 620 mg per capsule of Laminine. OPT9™ contains the natural combination of power nutrients that include amino acids, glycopeptides, and oligopeptides that come from a nine-day old partially incubated and fertilized eggs. It also has isolated plant proteins, and marine elements that work together to form a super food ensuring us of a healthy mind and body and overall well-being.
OPT9™ or Oligopeptide Transporter 9 is a combination of nutrients derived from natural and organic sources. The formula includes amino acids, glycopeptides, and oligopeptides that come from the whites of a 9-day old fertilized avian egg. Together with the extract, Laminine contains isolated plant proteins and marine elements that work together to form a super food for the mind and body.
Effect of OPT9™ in the body
OPT9’s active ingredient is known as FibroBlast Growth Factor (FGF) which is clinically proven to positively influence aging or damaged cells. Together with other component that includes amino acids, help the skin to normalize to its best level. It also affects and boosts nutrients that affects our hair, memory function and cardiovascular system. These come from natural sources such as plant protein and marine or protein or known as sea-vegetables. These symbiotic ingredients are extracted and combined to form what is perhaps the best food supplement that has ever been discovered.
PESE – The egg extract process
Laminine’s unique ingredient is derived from a 9-day old fertilized hen eggs. The avian eggs are incubated until they reach the critical moment of pre-embryonic stage fertilization, where rapid cellular growth is activated. After the 9th day, the fertilized egg is transformed into an environment containing all the necessary elements to develop a living organism, containing the highest amount of nutrition and protection.
The incubation also supports the development of key nutrients to highest concentrations, creating a unique combination of Amino Acids, Oligopeptides and Glycopeptides. At this precise stage, the highly potent tissue is extracted from the egg during its Photo Embryonic Stage or PES.
The Photo Embryonic Stage Extract (PESE) is the foundation of Laminine. A patented process which extracts the critical nutritional fluid from the white of an egg at this stage (Photo-embryonic stage). The extraction should and can only be done at exactly the ninth day, not earlier or later.
In fact, the precise hour or even second is critical when extracting the nutritional fluid. At this stage, no “bird” form has evolved yet. PESE has its origins on Dr. Bjodne Eskeland’s perfection of YTE (Young Tissue Extract). It is the most important ingredient of Laminine.
It is derived from fertilized hen eggs that are incubated just until they reach the pre-embryonic stage. As the eggs approach this stage, biological substances are activated that exhibit favorable metabolic properties. This substance which is biological in nature are from protein fractions extracted at a precise point in the egg’s development. When the key nutrients reach their peak of concentration. YTE is extracted in Norway, which has the reputation to be one of the few countries that remain Salmonella-free.
The Young Tissue Extract is in powder form. A protein that has been clinically proven to provide a great four fold benefits to our human body. The effects to our system are basically categorized in an increased in sexual health and desire; significant increase in stamina and energy; boost in muscle strength for sports activities, particularly beneficial to athletes, and affects our brain and body to relax, thus beneficial for people who are highly stressed.
PESE affects brain activity
Laminine is hailed as the ‘Happy Pill’ because it results in a happier mood. Laminine reduces the stress hormone cortisol and increases serotonin that encourages positive brain activities. While Laminine is not an antidepressant pill, its ability to reduce depression has been seen in clinical tests.
Laminine’s patented process isolates certain proteins which neutralize the benefits of the essential amino acids. The result is an ingredient, which is high in Glutamic acid, (further enhancing the cognitive function of the brain), branched chain amino acids (to counter insomnia), Lysine (to control the release of serotonin, controlling moods) and Arginine (promoting Nitric Oxide and growth hormone formation). These especially isolated proteins add a synergistically potent composition that has been found to enhance brain activity.
The high levels of Glycine in the specially extracted marine protein used in Laminine, combined with a significant amount of hydroxyproline to stabilize the glycine, makes it a primary candidate for a terrific brain food. By itself, Glycine is a neurotransmitter, primarily utilized by the brain to control glutamate levels. As a combination within OPT9, it becomes a powerful force to enhance memory function in the brain.
Photo Embryonic Stage Extract or PESE was the name assigned to Laminine’s core ingredient. It is the critical nutritional fluid found from the white of an egg (albumin) at the Photo Embryonic Stage (PESE Extract) on the 9th day. The extract not only provided a mechanism of rapid transport of very critical nutrients, but also contained Basic Fibroblast Growth Factor, which is most probably responsible for the amino acids and peptides to be utilized in the right manner, by “directing” their correct use in the body.
The growth factor is also responsible for nurturing the body’s own stem cells both differentiated, and undifferentiated. Common amino acid formulations do not contain this growth factor, and may not be utilized by the brain in the most efficient manner.
PESE contains the most potent and balanced combination of not only amino acids, but also Fibroblast Growth Factor or FGF. We believe amino acids derived from such fluids combined with the growth factors are able to enhance brain function because they are “precisely” engineered to support the most complex stage of birth of a living creature, the beginning. This beginning is the most critical stage in our development just like the take-off is the most complex function in flying an airplane, or the foundation in construction is the most essential function in the life of a building.
FGF in PESE
The health benefits of the hen egg have been known for centuries. Recently, further investigation of the mechanism of the development of an embryo in an egg during incubation revealed the scientific equivalent of the “miracle of life”. The potency of the nutrients available to the embryo at the latter stage of development stage has always been assumed to be high, but it was only recently that the chemical structure of the original egg solids for these critical stages was obtained.
Additionally, the uptake of the Fibroblast Growth Factor (FGF) present in PESE by the embryo sharply increases and the FGF present have been isolated through a patented process precisely at the right stage of incubation, extracted and freeze dried to bring the “miracle of life” benefits to humans. Extracting PESE before the peptides and FGF are “used up” to build organs and bones, allows us to provide this building, repairing, maintenance mechanism of perfectly balanced amino acids, peptides and growth factors to humans. While virtually unknown in the United States until very recently, PESE has been sold successfully as a high-value nutritional supplement in Europe for many years.
Oligopeptide: Extended benefits of FGF
FGF that contains Oligopeptide (also called peptide, ‘oligo’ means few) consists 2 and 20 amino acids (building blocks of proteins) that includes dipeptides, tripeptides, tetrapeptides, pentapeptides. It is a rich blend that can be interpreted as building blocks having no one to guide them or bridge to get them where needed. FGF acts as its bridge or director” giving direction where it should go. This is precisely why Laminine food supplement seem to cure nearly all types of ailments and sickness. Thus it is to surmise that the role of Fibroblast Growth Factor is to be the “director. . In 1988, a day-by-day study was performed and showed that FGF is prolific in PESE, as well as in human placenta.
Peptides are short chains of amino acid which is bonded by peptide. Peptides are distinguished from proteins on the basis of size. FGF was only discovered in the 1970s and is also a peptide which is critical in the development of embryos, including a human being. However, it is not found to be circulating in the human adult bodies. FGF is responsible for building the linings in the blood vessels, creating the infrastructure for the nutrients to flow to critical areas of the brain and organs. Research gives to credit FGF as it can affect many neuro-disorders. There were clear results showing that FGF can affect the growth of neurites. Neurites are signal senders (Axons) and signal receivers (dendrites) attached to the brain neurons.
Research also showed clearly that new cell cultures show a dramatic increase in peptide and amino acid boost in the presence of Fibroblast Growth Factors (FGF). This result validates the hypothesis that embryonic growth (eggs or humans) is influenced by a very precise mechanism, which combines unique combinations of amino acids, peptides and FGF.
In 1962, it was discovered that neural stem cells are formed by the body in response to abnormalities, and are resident in certain zones of the brain. The brain is therefore ready to repair the damage. These cells have shown to differentiate into a wide range of neurons. Neurons derived from such neural stem cells are capable of migrating to various regions of the Central Nervous System. Thus indeed, our body has the ability to heal itself, where stem-cells are present, formed naturally in our body. Being infused with more stem cells are of course another topic.
Lysine (Lys or K) is an amino acid essential for humans known to regulate serotonin levels in our brain. Laminine contains the amino acid Lysine that is derived from the PESE and other vegetable proteins. The combination of these components delivers a higher level of Lysine in the OPT9 (combination formula exclusive to Laminine) than either ingredient would have plenty by itself. Lysine is known to regulate serotonin levels in the brain.
It is estimated that about 20 million people across the globe suffer from several forms and grades of depression. Many are prescribed to certain drug prescriptions such as Prozac. However, there are several side effects from these prescription drugs including sexual dysfunction. Some doctors estimate that the number of people experiencing side effects from drugs may be as high as 70%. Contrary however to the Lysine or other components found in Laminine Food Supplement, clinical studies have shown that Laminine enhances libido or sexual drives among its regular users. Percentage to date is as high as 80%.
Above this, of course, those taking Laminine report improvement in their mood and an increased ability to manage stress on a daily basis. They begin to be driven again and inspired to accomplish and become things and be more productive.
Vegetable protein has an essential amino acid profile, which is very close to that of the ideal protein for human nutrition (FAO/WHO 1985 and 2002). For Laminine™, a patented process further isolates these proteins to eliminate the compounds, which neutralize the benefits of the essential amino acids.
The result is an ingredient, which is high in Glutamic acid, (further enhancing the cognitive function of the brain), branched chain amino acids (to counter insomnia), Lysine (to control the release of serotonin, controlling moods) and Arginine (promoting Nitric Oxide and growth hormone formation). These especially isolated proteins, therefore, adds a synergistic potent composition to enhance brain activity.
Use of Marine Proteins
The high levels of Glycine found in selected marine protein are extracted and added in Laminine. This is combined with a significant amount of hydroxyproline to stabilize the glycine. This process, in turn, elevates it to become the primary candidate for a super-brain food. Glycine in itself is a neurotransmitter, primarily utilized by the brain to control glutamate levels. As a combination within the OPT9 formula, the mix enables it to become a potent nutrient to enhance our brain and memory function. Thus Laminine becomes a holistic supplement, supporting not only the body tissue but providing nutrients to our brain as well.